Olema Oncology is a cancer medicines company dedicated to impacting breast cancer and beyond. Our lead program, palazestrant (OP-1250), is a differentiated oral medicine known as a complete estrogen receptor antagonist (CERAN) initially in development for metastatic breast cancer. Our pipeline also includes OP-3136, a potent, selective oral inhibitor of the KAT6 pathway. At Olema, we are building a focused team committed to our mission with intention and clarity. Working alongside a talented passionate group of leaders and advisors, we strive to create better medicines that aim to help patients feel better, longer. For more information, visit us at www.olema.com.About the Role >>> Senior Director of IT Infrastructure, Operations, and Help Desk As the Senior Director of IT Infrastructure, Operations, and Help Desk reporting to the Vice President, Information Technology, you will be a critical leader within Olema's IT organization. This individual will be responsible for overseeing the company's infrastructure and operational IT services with a primary focus on managing and enhancing the Help Desk function. The role will ensure that user onboarding/offboarding, service delivery, and day-to-day support are executed with excellence and in alignment with ITIL best practices. A strong emphasis on user experience, operational metrics, continuous improvement, coaching, team development, and compliance frameworks (e.g., SOX, HIPAA, GDPR, GxP) is essential. This role is based out of our San Francisco office and will require 10% travel. Your work will primarily encompass: Provide strategic leadership and hands-on management of the Infrastructure, Operations, and Help Desk functions. Lead and mentor the Director of Infrastructure and Help Desk team to deliver outstanding user support and system reliability. Oversee user onboarding and offboarding processes, ensuring a seamless and compliant user experience. Implement and manage an ITIL-based service management framework, including incident, request, problem, change, and asset management. Develop and monitor KPIs and SLAs for Help Desk and IT operations, creating a metrics-driven organization. Lead the development of IT roadmaps for infrastructure, operations, and end-user services to align with business goals. Provide hands-on technical leadership when necessary to troubleshoot complex issues and support the team. And will also include: Ensure adherence to regulatory requirements, company policies, and security standards. Partner with Information Security, Compliance, and Legal to ensure controls necessary for SOX, HIPAA, GDPR, and GxP compliance are in place. Manage vendor relationships for infrastructure, SaaS applications, and outsourced services. Foster a high-performance team culture with strong coaching, development, and mentorship practices. Drive the continuous improvement of ticketing systems such as Fresh Service, including workflows, automation, and reporting. Serve as a champion for user experience, ensuring IT services are efficient, intuitive, and customer focused. Act as escalation point for major incidents and critical operational issues. Evaluate and implement AI-driven tools to improve IT operations, Help Desk automation, and service delivery. Stay informed of emerging and AI technologies and assess their applicability to enhance infrastructure and user support functions. Ideal Candidate Profile >>> A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role. Knowledge: Bachelor’s degree in computer science, Information Systems, or a related field required; master's degree preferred. ITIL Foundation Certification required; ITIL Intermediate or Expert Certification highly preferred. Additional certifications such as PMP, Six Sigma, or COBIT are advantageous. Deep understanding of service management principles, and operational excellence practices. Service, ServiceNow, or Jira Service Management. Proven success developing IT roadmaps that align technology strategy with business objectives. Proficiency with modern infrastructure environments, including cloud services (AWS, Azure), SaaS, network management, cyber, endpoint management, and MDM. Experience: 10+ years of progressive IT leadership experience with a strong focus on infrastructure, IT operations, and end-user support, with a minimum of three years of people management experience. 5+ years directly managing Help Desk or End User Services teams. Ability to serve as a hands-on technical leader when needed, providing direct support and troubleshooting complex infrastructure or user issues. High-level coaching, mentorship, and team development skills to build a strong, engaged, and high-performing team. Demonstrated experience managing compliance requirements within highly regulated environments (SOX, HIPAA, GDPR, GxP). Proficient in Microsoft technologies. Experience with deploying or managing AI technologies in IT operations, such as chatbots, intelligent automation, or predictive analytics. Experience implementing metrics and reporting to drive Help Desk performance and user satisfaction. Outstanding communication, organizational, leadership, and customer service skills. Proven ability to prioritize and manage multiple complex initiatives in a dynamic, fast-paced environment. Preferred Experience: Prior experience in biotech, pharmaceutical, or life sciences organizations. Familiarity with 21 CFR Part 11 and FDA guidelines regarding computer system validation. Knowledge of Agile/Lean IT operations and DevOps principles. Experience supporting hybrid/remote workforces. Attributes: Strong commitment to excellence and delivering outstanding user experiences. Highly analytical and data-driven decision-maker. Proactive, self-motivated, and results-oriented with a 'bias for action'. Collaborative team player who thrives in a cross-functional environment. Flexible and adaptable to evolving business needs and technology trends. The base pay range for this position is expected to be $257,000-$270,000 annually, however the base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits. #LI-MT1Important Information >>> We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated. We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants. Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you. Additional Note/Fraud Alert: Olema will not conduct interviews via text message or messaging platforms and will not ask you to download anything as part of your interview. Though we use third party tools to help with advertising our jobs, please be vigilant in checking that the communication is in fact coming from Olema.
Job Type
Onsite role
Skills required
No particular skills mentioned.
Location
San Francisco, California
Salary
257,000-270,000
Date Posted
May 9, 2025
Olema Oncology is seeking a Senior Director of IT Infrastructure, Operations, and Help Desk to lead and enhance IT services, focusing on user experience and compliance. The role requires strategic leadership and hands-on management in a dynamic environment.